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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 9.7
Human Site: S1046 Identified Species: 13.33
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S1046 T E H L V T K S R L P L R A Q
Chimpanzee Pan troglodytes XP_507923 1056 119132 S1046 T E H L V T K S R L P L R A Q
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 N846 E R E Q E L Q N L L E V I T L
Dog Lupus familis XP_534964 1334 149091 R1327 T T E H S V T R S R L P L R A
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S1042 S D L S I S K S R L P L H T S
Rat Rattus norvegicus O55165 796 89797 P789 M A S A P L H P A T V V D H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 E1190 A S L L V R D E E S Q E N Q L
Frog Xenopus laevis P28025 1060 119314 K1051 E V D Q A L T K S K L P L R M
Zebra Danio Brachydanio rerio NP_775368 955 106984 L948 E Y M Y P R V L S R P R S R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 P1046 S L S R S L T P S K T S P R G
Honey Bee Apis mellifera XP_623508 706 80766 K699 P V S N N I L K E E A I D A S
Nematode Worm Caenorhab. elegans P46873 699 78760 R692 Q S A K R P P R L A S L N P K
Sea Urchin Strong. purpuratus P46872 699 78679 S692 K K Q A S M A S S I D A L L Q
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 A1048 D I K H V A A A F E A A Q S L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 F1033 H N A N L G P F L V M M V C D
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 E1096 T E P I L K G E E T E N N D I
Red Bread Mold Neurospora crassa P48467 928 102392 S921 N P P E N K R S S W F F Q K S
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 6.6 N.A. 40 0 N.A. N.A. 13.3 0 6.6 N.A. 0 6.6 6.6 13.3
P-Site Similarity: 100 100 26.6 6.6 N.A. 66.6 6.6 N.A. N.A. 13.3 0 13.3 N.A. 6.6 13.3 13.3 26.6
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 0 13.3 6.6
P-Site Similarity: 26.6 N.A. N.A. 20 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 12 12 6 6 12 6 6 6 12 12 0 18 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % C
% Asp: 6 6 6 0 0 0 6 0 0 0 6 0 12 6 12 % D
% Glu: 18 18 12 6 6 0 0 12 18 12 12 6 0 0 6 % E
% Phe: 0 0 0 0 0 0 0 6 6 0 6 6 0 0 0 % F
% Gly: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 6 % G
% His: 6 0 12 12 0 0 6 0 0 0 0 0 6 6 0 % H
% Ile: 0 6 0 6 6 6 0 0 0 6 0 6 6 0 6 % I
% Lys: 6 6 6 6 0 12 18 12 0 12 0 0 0 6 6 % K
% Leu: 0 6 12 18 12 24 6 6 18 24 12 24 18 6 18 % L
% Met: 6 0 6 0 0 6 0 0 0 0 6 6 0 0 6 % M
% Asn: 6 6 0 12 12 0 0 6 0 0 0 6 18 0 0 % N
% Pro: 6 6 12 0 12 6 12 12 0 0 24 12 6 6 0 % P
% Gln: 6 0 6 12 0 0 6 0 0 0 6 0 12 6 18 % Q
% Arg: 0 6 0 6 6 12 6 12 18 12 0 6 12 24 0 % R
% Ser: 12 12 18 6 18 6 0 30 36 6 6 6 6 6 18 % S
% Thr: 24 6 0 0 0 12 18 0 0 12 6 0 0 12 0 % T
% Val: 0 12 0 0 24 6 6 0 0 6 6 12 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % W
% Tyr: 0 6 0 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _